Defective Drugs – Paxil

Paxil is a strong antidepressant drug manufactured by GlaxoSmithKline and belongs to the class of drugs known as selective seratonin re-uptake inhibitors (SSRIs). The drug works by blocking the re-absorption of seratonin in the brain. Seratonin is a neurotransmitter that helps to maintain positive emotions. Paxil is used to treat depression, as well as generalized anxiety disorder, panic disorder, social anxiety disorder and obsessive-compulsive disorder.

The drug became available in the United States in 1993 and since then it has become clear that Paxil has some serious side affects when taken in combination with other drugs. Mixing Paxil with monoamine oxdiase inhibitors can cause serious side effects, such as extreme agitation, delirium and even lead to a coma. Mixing Paxil with tryptophan can cause headaches, nausea, dizziness and sweating. Taking Paxil with alcohol can potentially lead to mental and motor impairment. Also, patients have been warned to consult with a doctor or pharmacist prior to taking Paxil with Warfarin, Sumatriptan, Tridcycle antidepressants and Lithium.

The issue of mixing the drugs is a major problem, as people with the disorders that necessitate taking Paxil are frequently also taking some of the other drugs listed above. There may have been labeling and testing inconsistencies at GlaxoSmithKline and patients may be eligible for compensation from the drug maker.